Ad-Dawaa' Journal of Pharmaceutical Sciences

Recent Updates on the Potential of Medicinal Plants from Indonesia as Anti-Atherosclerotic Agents

Gayuk Kalih Prasesti — 2024-11-30

Atherosclerosis is one of the causes of problems in the cardiovascular system. This condition can be prevented by using natural products, one of which is medicinal plants. This review collects data on medicinal plants that are easily found in Indonesia that can reduce or improve atherosclerosis conditions. There are 10 plants reviewed that have a high level of safety and potential to be developed as medicine. The plant parts used are fruit and leaves. Some are commonly used as cooking spices such as turmeric and garlic which are found to be useful for improving atherosclerosis conditions. In the context of modern drug development, Indonesia holds significant potential for exploring these plants as sources of active compounds for pharmaceutical applications. Scientific studies of these natural materials are crucial for identifying bioactive components and understanding their mechanisms of action. With the right approach, Indonesia's natural resources could form the basis for developing new, safer, and more effective drugs. Additionally, Indonesia has a considerable opportunity in the global market for natural health products, including nutraceuticals and dietary supplements, as global interest in natural health solutions continues to grow.

Comparison of Tannin Levels in Brewed and Boiled Green Tea (Camellia Sinensis (L.) Kuntze) by the Method of UV-Vis Spectrophotometry

Anita Agustina Styawan — 2024-11-29

Green tea (Camellia sinensis (L.) Kuntze) has antibacterial and antioxidant properties that are effective in preventing and treating diseases. Green tea contains tannin compounds with antidiarrheal properties, stops bleeding and prevents inflammation of the oral mucosa. To get its properties, the way tea is processed affects the tannin content in tea. The research method used was experimental research. The sample used was green tea taken from the cultivation site "Mbok Karti" Kemuning, Ngargoyoso, Karanganyar. Extracted using the reflux method. Determination of levels analyzed by UV-Vis Spectrophotometry method. Qualitative test results using FeCl3 1% that brewed and boiled green tea contains tannins by showing a change in color to blackish green. The results of quantitative tests using UV-Vis Spectrophotometry obtained a comparison of tannin levels in brewed green tea of 0.05163% w/b and boiled ones of 0.04988% w/b. Where in every 200 grams of brewed green tea samples there are 103.26 mg of tannins for boiled green tea samples there are 99.67 mg of tannins. Tannin levels in brewed green tea are greater than those boiled because tannins are damaged at temperatures above 80°C. While when boiling uses temperatures above 80°C. Whereas when boiling uses temperatures above 80°C. So it is concluded that brewed green tea has higher tannin levels than boiled green tea.

Identification of Pathogenic Bacteria in Liquid Waste from "X" Hospital in Kediri City

Tri Ana Mulyati — 2024-11-29

Introdiction: Hospitals can not only be a place for people to seek treatment, but they can also get diseases, especially infectious diseases. One source of the spread of infectious diseases comes from hospital waste, so proper waste processing is needed. Hospital wastewater contains many pathogenic bacteria such as Enterobacter cloacae, Bacillus sp., Kluyvera sp., Enterobacter sakazaki, Klebsiella oxytoca and E.coli. This makes it necessary to manage hospital wastewater to prevent the spread of disease, especially by pathogenic bacteria. On the other hand, research is still needed on the specific types of bacteria found in wastewater, including hospitals in Kediri City. Aims: to determine the types of pathogenic bacteria at the "X" hospital in Kediri City. Result: the density of bacteria in the bottom waste was greater than in the top and middle parts, with an average of 1,830 bacteria/100 ml. The results of the identification test showed that pathogenic bacteria contained in the waste from hospital "X" in Kediri City included Klebsiella (25%), E.coli (50%) and Pseudomonas (25%). Conclusion: The waste from "X" Hospital Kediri City contains three types of pathogenic bacteria: Klebsiella, E. coli, and Pseudomonas.