MICROORGANISMS AS RISK FACTORS AND PROTECTION OF WOMEN'S REPRODUCTIVE HEALTH: AN ANALYSIS OF THE CURRENT LITERATURE
Keywords:
Bacterial vaginosis, probiotics, vaginal microbiota, women’s reproductive health, sexually transmitted infections.
Abstract
Women’s reproductive health is significantly influenced by the intricate relationship between microorganisms and the body, where both pathogenic and beneficial microorganisms play critical roles. Pathogenic microorganisms, such as Chlamydiatrachomatis, Neisseria gonorrhoeae, and Gardnerella vaginalis, are often associated with reproductive tract infections, leading to conditions such as bacterial vaginosis (BV) and sexually transmitted infections (STIs). These conditions increase risks for serious complications, including infertility and pregnancy-related issues. On the other hand, beneficial microorganisms, especially Lactobacillus species, contribute to vaginal health by maintaining an acidic pH and producing antimicrobial substances that protect against pathogenic invasions. This review discusses the role of microorganisms as both risk factors and protective agents in women’s reproductive health. Addressing the impact of hormonal variations, hygiene practices, contraception, and lifestyle factors on vaginal microbiota composition. Furthermore, the potential of probiotic therapy to restore microbiota balance and prevent infections is explored. Understanding these dynamics may inform more targeted and effective therapeutic strategies to promote reproductive health. Additional research is needed to optimize probiotic therapies, develop personalized interventions, and leverage advancements in multi-omics technologies to further elucidate microbiota-health interactions.
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References
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Han, Y., & Ren, Q. ling. (2021). Does probiotics work for bacterial vaginosis and vulvovaginal candidiasis. In Current Opinion in Pharmacology (Vol. 61, pp. 83–90). https://doi.org/10.1016/j.coph.2021.09.004
Hardy, L., Jespers, V., De Baetselier, I., Buyze, J., Mwambarangwe, L., Musengamana, V., Van De Wijgert, J., & Crucitti, T. (2017). Association of vaginal dysbiosis and biofilm with contraceptive vaginal ring biomass in African women. PLoS ONE, 12(6). https://doi.org/10.1371/journal.pone.0178324
Haya, J., García, A., López-Manzanara, C., Balawi, M., & Haya, L. (2014). Importance of Lactic Acid in Maintaining Vaginal Health: A Review of Vaginitis and Vaginosis Etiopathogenic Bases and a Proposal for a New Treatment. Open Journal of Obstetrics and Gynecology, 04(13), 787–799. https://doi.org/10.4236/ojog.2014.413109
Hickey, D. K., Patel, M. V., Fahey, J. V., & Wira, C. R. (2011). Innate and adaptive immunity at mucosal surfaces of the female reproductive tract: Stratification and integration of immune protection against the transmission of sexually transmitted infections. In Journal of Reproductive Immunology (Vol. 88, Issue 2, pp. 185–194). https://doi.org/10.1016/j.jri.2011.01.005
Hornung, S., Thuong, B. C., Gyger, J., Kebbi-Beghdadi, C., Vasilevsky, S., Greub, G., & Baud, D. (2015). Role of Chlamydia trachomatis and emerging Chlamydia-related bacteria in ectopic pregnancy in Vietnam. Epidemiology and Infection, 143(12), 2635–2638. https://doi.org/10.1017/S0950268814003616
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Published
2024-12-24
How to Cite
Hafsan, Hafsan, Ayu Febriyanti, Andi Nur Hanisa, and Sabilla Suryaning Amanda. 2024. “MICROORGANISMS AS RISK FACTORS AND PROTECTION OF WOMEN’S REPRODUCTIVE HEALTH: AN ANALYSIS OF THE CURRENT LITERATURE”. JURNAL SIPAKALEBBI 8 (2), 65-87. https://doi.org/10.24252/sipakallebbi.v8i2.52053.
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