Formulation of Film Soap Ethanol Extract Mesocarp of Red Watermelon (Citrullus lanatus) and Antioxidant Activity Test
Abstract
Film soap is soap in the form of a thin layer having a thickness of 100 - 500 µm made of foaming film and plasticizer. The advantages of paper soap preparations are convenient in use, hygienic, practical, and easy to carry anywhere. Mesocarp red watermelon is a part of watermelon that contains flavonoid compounds that have antioxidant activity. The purpose of this study was to formulate the film soap of red watermelon mesocarp extract and to determine its antioxidant activity. In this study, the formulation was carried out by making four formulas with varying concentrations of ethanol extract mesocarp of red watermelon F0 = 0%; F1 = 1.5%; F2 = 2% and F3 = 3%. The evaluation was carried out in the form of organoleptic examination, pH, foam power, weight uniformity, moisture content, thickness, irritation test, stability and antioxidant activity tests. The evaluation results of the film soap from the four formulas were pH 9.29 - 9.12; weight uniformity 0.125 - 0.134 grams, water content 16.80 - 16.30%; thickness 0.14 - 0.15 mm and physically stable. The antioxidant activity of each formula was seen from the value, namely IC50F0 = 76.42µg / mL; F1 = 70.36 µg / mL; F2 = 65.14µg / mL; F3 = 62.14 µg / mL. From the research results, it can be concluded that the ethanol extract of red watermelon mesocarp can be formulated into film soap and has antioxidant activity which is included in the strong group.
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References
Aktalis, I.Y. (2018). Formulasi Sediaan Sabun Mandi Padat Ekstrak Etanol Daun Afrika (Vernonia amygdalina). Karya Tulis Ilmiah. Kupang : Politeknik Kemenkes Kupang.
Anggai RA, Hasan H, Thomas N. (2013). Formulasi dan Evaluasi Sediaan Mikroemulsi Ekstrak Etanol Beras Merah (Oryza nivara) sebagai Antioksidan.KIM Fakultas Ilmu Kesehatan dan Keolahragaan, 1-11.
Amasa W, Santiago D, Mekonen S, Ambelu, A. (2012). Are Cosmetics used in Developing Countries Safe Use and Dermal Iritation of Body Care. Journal Of Toxicology; 2012 :1-8.
Anantia, R., Desnita, R, & Luliana, S. (2019). Pengaruh Penggunaan PEG 400 dan Gliserol sebagai Plasticizer terhadap Sifat Fisik Sediaan Patch Ekstrak Etanol Herba Pegagan (Centella asiatica (L) Urban).Jurnal Farmasi & Fakultas Kedokteran. 4 (1).
Departemen Kesehatan Republik Indonesia. (1980). Materia Medika Ed IV. Jakarta, Departemen Kesehatan RI.
Departemen Kesehatan Republik Indonesia. (2014). Farmakope Indonesia, Edisi V. Jakarta:Direktorat Jenderal POM.
Habibah, A., Cahya, G., Darma, E., & Gadri, A. (2011). Pengaruh Natrium Alginat dan HPMC Sebagai Basis terhadap Karakteristik Fisik Sediaan Film Soap yang Mengandung Serai Wangi (Cymbopogon winterianus joqitt). Prosiding Farmasi 5(2), 379 – 385.
Harmely,F., Deviarny, C & Yenni, W. S. (2015). Formulasi dan Evaluasi Sediaan Edible Film dari Ekstrak Daun Kemangi (Ocimum americanum L.) sebagai Penyegar Mulut. Jurnal Sains Farmasi & Klinis, 1(1), 38.
Mariani, S., Rahman, N., & Supriadi, S. (2018). Uji Aktivitas Antioksidan Ekstrak Buah Semangka (Citrullus lanatus). Jurnal Akademika Kimia, 7(3), 107.
Muchtar, H., Juwita,A., Putri,K. (2020). Uji Antioksidan Ekstrak Etanol Kulit Buah dan Daging Buah Menteng (Baccaurea racemosa (Blume) Mull. Arg.) dengan Metode DPPH (2,2 diphenyl-1-picrylhydrazyl). Jurnal Farmasi dan Kesehatan.
Mujahidah, U., Aryani, R., & Suparman, A. (2013). Formulasi dan Evaluasi Sediaan Film soap Antikbakteri yang Mengandung Ekstrak Kulit Luar Kacang Tanah ( Arachis hypogaea L .) dan Uji Aktivitas Terhadap Bakteri Propionibacterium acnes. Prosiding Farmasi, 5(2), 61- 66.
Poucher, W. A. (1993). Poucher’s Perfumes Cosmetics and Soap.Charman and Hall.
Putri, A.M. (2020). Perbandingan Aktivitas Antioksidan Terhadap Biji Bunga Matahari (Halianthus annus L.) Dengan Tumbuhan Lainnya. Journal of Research and Education Chemistry, 2 (02), 85 - 91
SNI, (1996). Sabun Mandi Cair, 06-0485-1996. Jakarta : Standar Nasional Indonesia
Ulfa, A. M., Chusniasih, D., & Bestari, A. D. (2019). Pemanfaatan Potensi Antioksidan dari Limbah Kulit Buah Kakao (Theobroma cacao L ). Jurnal Farmasi Malahayati, 2(1).
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