The Evaluation of Loose Powder Formulation of Manihot Starch and Maydis Starch with Natural Orange Sweet Potato

  • Kris MonikaYanti Monika Institut Teknologi Bandung
    (ID) https://orcid.org/0000-0002-9504-5740
  • Putu Indra Sekolah Tinggi Farmasi Mahaganesha
    (ID)
  • Ni Luh Sanjiwani Putri Pasha Institut Teknologi Sumatera
    (ID)
Keywords: Manihot starch, maydis starch, loose powder, Ipomea batatas L, physical properties

Abstract

Introduction: Starch is an inert additive and can be mixed with almost all drugs without causing a reaction. The use of natural dyes has a better level of safety compared to synthetic dyes. Objective: Comparing the physical evaluation of loose powder preparations made from maydis starch with manihot starch and the use of a natural dyes in the form of orange sweet potato. Method: Making orange sweet potato tuber extract using meseration and the solvent ethanol (95%): acetone (98%) (5:5). Then the powder preparation is made and a physical evaluation is carried out in the form of organoleptics, particle size distribution, homogeneity, humidity and flow rate. Results: The results show that the organoleptic test for each formula is good, the distribution of F2 particles is the best, the homogeneity test for each formula is good, the humidity test is that F1 is higher than F2 by 1.05 ± 0.01%, the flow speed test for F2 is better than F1 namely 23.53 ± 0.35 g/sec. Conclusion: Powder preparations made from Manihot starch are better than powder preparations made from Maydis starch.

Downloads

Download data is not yet available.

References

A. T. Daru, M. Abdassah, A. Subarnas. (2019). Bahan Dasar Sediaan Kosmetik Bedak Pelindung Kulit Wajah dari Pati Temulawak (Curcuma xanthorriza Roxb). Journal of Science, Technologi and Enterpreneur: 1(12).147-161.
Abdul Rahim. (2020). The Combination Of Green Beans And Corn Amylum As A Tablet Destroying Material. The 2nd Alauddin Pharmaceutical Conference and Expo (ALPHA-C). DOI: https://doi.org/10.24252/kesehatan.v1i1.18470
Depkes RI. (2020). Farmakope Indonesia edisi VI. Departemen Kesehatan. Republik Indonesia. Jakarta: Kementrian Kesehatan Republik Indonesia.
Devi,I.A.S., Q.A. Shodiquna, N.W.S.D.Eni, C.I.S. Arisanti, P.O. Samirana. (2018). Optimasi Konsentrasi Polivinil Pirolidon (PVP) sebagai Bahan Pengikat tehadap Sifat Fisik Tablet Ekstrak Etanol Rimpang Bangle (Zingiber cassumunar Roxb). Jurnal Farmasi Udayana: 7(2).
Dewi, S.P.P., Prasetia, I.G.N.J.A., Arisant i, C.I.S. (2021). Pengaruh Amilum Manihot Partially Pregelatinized Sebagai Penghancur Intragranular – Ektragranular pada Formulasi Tablet Ekstrak Daun Ubi Jalar Merah (Ipomoea batatas L.). J Ilmiah Medicamento. 7 (1): 62-70, Doi: https://doi.org/10.36733/medicamento.v7i1.674.
Erliana Ginting. (2013). Carotenoid Extraction Of Orange-Flashed Sweet Potato And Its Application As Natural Food Colorant. J Teknologi dan Industri Pangan: 24(1). 81-88. Doi: https://doi.org/10.6066/jtip.2013.24.1.81
Isriany Ismail, Surya Ningsi, Nurshalati Tahar, Aswandi. (2014). Pengaruh Jenis Pengikat Terhadap Sifat Fisika Sediaan Serbuk Masker Wajah Kulit Buah Semangka (Citrullus vulgaris schrad). JF FIK UINAM: 2(2).
L. Lachman, H. A. Lieberman and J. L. Kanig. (2008). Teori dan Praktek Farmasi Jilid 2. Jakarta: UI PRESS.
M. E. Aulton. (2002). Pharmaceutics : the science of dosage form design. New York: Churchill Livingstone.
P. J. Sinko. (2011). Martin Farmasi Fisika Dan Ilmu Farmasetika. Jakarta: EGC
R. C. Rowe and P. J. Sheskey. 2009. Handbook of Pharmaceutical Excipients, 6th ed. London: Pharmaceutical Press and American Pharmacists Assosiation.
Rinawati, Zipora Sembiring, Wasinton Simanjuntak, Emantis Rosa. (2021). Pembuatan Serbuk Pewarna Alami Dari Berbagai Tanaman Tropis Dengan Metode Oven Drying. J. Pengabdian Kepada Masyarakat Tabikpun: 2(2). Doi: https://doi.org/10.23960/jpkmt.v2i2.20
Ruben Tinosa Dwika, Trisna Ceningsih, Setia Budi Sasongko. (2012). Pengaruh Suhu dan Laju Alir Udara Pengering pada Pengeringan Karaginan Menggunakan Teknologi Spray Drayer. J Teknologi Kimia dan Industri: 1(1).
Sarina Efendi, Ansharullah, Muh. Syukri S, Sri Wahyuni, Sri Rejeki. (2022). Effect of yellow sweet potato (Ipomoea batatas L) flour and carrot (Daucus carota) filtrate formulation on organoleptic characteristics and nutritional value of wet noodles. J. Sains dan Teknologi Pangan: 7(2), 5521-5535.
Wasitaatmadja, S.M. (1997). Penuntun Ilmu Kosmetik Medik. UI- Press. Jakarta.
Yudianto. (2004). Pengaruh Variasi Kombinasi Amilum Jagung {Zea May, L) dan Avicel PH 101 Terhadap Waktu Hancur dan Disolusi Tablet Paracetamol. Skripsi: Fakultas MIPA Jur Farmasi UH Jogjakarta.
Yuningsih, Hadi Susilo, Yusransyah. (2020). Formulasi Dan Uji Stabilitas Fisik Bedak Tabur Ekstrak Etanol Daun Kapuk Randu (Ceiba pentandra(L.) Gaertn.). J Ilmiah Kesehatan Delima: 2(2), 137-154. Doi: 10.31793/1680-1466.2020.25-4.291.
Published
2023-12-31
How to Cite
Monika, K. M., Dewi, P. I. C., & Pasha, N. L. S. P. (2023). The Evaluation of Loose Powder Formulation of Manihot Starch and Maydis Starch with Natural Orange Sweet Potato. Ad-Dawaa’ Journal of Pharmaceutical Sciences, 6(2), 173-181. https://doi.org/10.24252/djps.v6i2.47656
Section
Artikel
Abstract viewed = 64 times

Most read articles by the same author(s)