Potential of Secang Wood (Caesalpinia sappan L.) Ethanol Extractas Anti-Oxidant and Sun-Protection

  • Mutista Hafshah UIN Walisongo Semarang
    (ID)
  • Alfiatu Rohmah UIN Walisongo Semarang
    (ID)
  • Ana Mardliyah UIN Walisongo Semarang
    (ID)

Abstract

Although sunlight has numerous health benefits, prolonged direct exposure to the sun can be harmful to the skin. Among the negative effects of sun exposure are redness and burning of the skin, as well as dullness, wrinkles, dryness, and premature aging, as well as skin cancer. The use of sunscreen to protect the skin from the harmful effects of prolonged sun exposure is becoming more widespread. On the other hand, some sunscreens contain potentially harmful chemicals such as isopropyl alcohol, DEA (diethanolamine), TEA (triethanolamine), and MEA (monoethanolamine), which can cause allergic reactions as well as kidney and liver disorders when used for an extended period of time. As a result, this investigation was carried out in order to determine the antioxidant potential of natural ingredients, specifically sappan wood (Caesalpinia sappan L.), using the DPPH method, as well as its potential as a sun-protective agent using an in vitro SPF test using ultraviolet-visible (Uv-Vis) spectrophotometry (Uv-Vis). The results revealed that the maceration method produced a 17.779 percent yield of ethanol extract of sappan wood, which was used in this study. The extract possesses extremely potent antioxidant activity, as evidenced by its IC50 value of 12,611 mg/L. Furthermore, based on the results of tests and the calculation of the SPF (sun protection factor) value, sappan wood extract has been shown to have potential as a sun protection agent. Using an extract concentration of 120 mg/L, the highest SPF value.

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Author Biography

Mutista Hafshah, UIN Walisongo Semarang

Program Studi Kimia

References

Altemimi, A., Lakhssassi, N., Baharlouei, A., Watson, D. G., & Lightfoot, D. A. (2017). Phytochemicals: Extraction, isolation, and identification of bioactive compounds from plant extracts. Plants, 6(4). https://doi.org/10.3390/plants6040042

Asfar, A. M. I. A., & Yasser, M. (2019). Analisis Kualitatif Fitikomia Kandungan Flavonoid Ekstrak Kayu Sepang (Caesalpinia Sappan L.) dari Ekstraksi Metode Ultrasonic Assisted Solvent Extraction. Chemica: Jurnal Ilmiah Kimia Dan Pendidikan Kimia, 19(2), 143. https://doi.org/10.35580/chemica.v19i2.12772

Csapó, J., Prokisch, J., Albert, C., & Sipos, P. (2019). Effect of UV light on food quality and safety. Acta Universitatis Sapientiae, Alimentaria, 12(1), 21–41. https://doi.org/10.2478/ausal-2019-0002

Ebrahimzadeh, M. A., Enayatifard, R., Khalili, M., Ghaffarloo, M., Saeedi, M., & Charati, J. Y. (2014). Correlation between sun protection factor and antioxidant activity, phenol and flavonoid contents of some medicinal plants. Iranian Journal of Pharmaceutical Research, 13(3), 1041–1048. https://doi.org/10.22037/ijpr.2014.1554

Febriyenti, F., Suharti, N., Lucida, H., Husni, E., Sedona, O., Farmasi, F., & Andalas, U. (2018). Karakterisasi dan Studi Aktivitas Antioksidan dari Ekstrak Etanol Secang (Caesalpinia sappan L.). 5(1), 23–27. 10.25077/jsfk.5.1.23-27.2018

Hendri Faisal, & Handayani, S. (2019). Comparison of Antioxidant Activity of Ethanol Extract of Fruit and Okra Leaves (Abelmoschus esculentus L. Moench) with DPPH and ABTS Methods. Indonesian Journal of Pharmaceutical and Clinical Research, 2(2), 6–13. https://doi.org/10.32734/idjpcr.v2i2.2815

Khalid, M., & Abdollahi, M. (2021). Environmental distribution of personal care products and their effects on human health. Iranian Journal of Pharmaceutical Research, 20(1), 216–253. https://doi.org/10.22037/ijpr.2021.114891.15088

Lailiyah, M., Saputra, S. A., & Sari, F. (2020). Antioxidant activity and sun protection factor evaluation for cream formulation of purified roasted corn silk extracts (Zea Mays L. Saccharata). Pharmaciana, 10(3), 371. https://doi.org/10.12928/pharmaciana.v10i3.17780

Lorensia, A., Suryadinata, R. V., & Fitrianingsih, N. (2020). Knowledge of sunlight exposure toward obesity in geriatric. Farmasains : Jurnal Farmasi Dan Ilmu Kesehatan, 2014(Vol 5, No 1 (2020)), 13–22. https://doi.org/10.22219/farmasains.v5i1.11454

Mekala, K., & Radha, R. (2015). A Review on Sappan Wood-A Therapeutic Dye Yielding Tree. Research Journal of Pharmacognosy and Phytochemistry, 7(4), 227. https://doi.org/10.5958/0975-4385.2015.00035.7

Nomer, N. M. G. R., Duniaji, A. S., & Nocianitri, K. A. (2019). KANDUNGAN SENYAWA FLAVONOID DAN ANTOSIANIN EKSTRAK KAYU SECANG (Caesalpinia sappan L.) SERTA AKTIVITAS ANTIBAKTERI TERHADAP Vibrio cholerae. Jurnal Ilmu Dan Teknologi Pangan (ITEPA), 8(2), 216. https://doi.org/10.24843/itepa.2019.v08.i02.p12

Parrado, C., Mercado-Saenz, S., Perez-Davo, A., Gilaberte, Y., Gonzalez, S., & Juarranz, A. (2019). Environmental Stressors on Skin Aging. Mechanistic Insights. Frontiers in Pharmacology, 10(July), 1–17. https://doi.org/10.3389/fphar.2019.00759

Pertamawati, P., Sriningsih, S., Fahrudin, F., & Efendi, J. (2017). Konsumsi Ekstrak Secang (Caesalpinia sappan L.) Terhadap Volume Urin Tikus Putih Jantan Galur Spraque Dawley. Jurnal Jamu Indonesia, 2(3), 121–126. https://doi.org/10.29244/jji.v2i3.41

Savoye, I., Olsen, C. M., Whiteman, D. C., Bijon, A., Wald, L., Dartois, L., Clavel-Chapelon, F., Boutron-Ruault, M. C., & Kvaskoff, M. (2018). Patterns of Ultraviolet Radiation Exposure and Skin Cancer Risk: the E3N-SunExp Study. Journal of Epidemiology, 28(1), 27–33. https://doi.org/10.2188/jea.JE20160166

Setyawaty, R., Dwiyanti, M., & Dewanto, D. (2020). Production of Compact Powder Blush on from Secang Wood (Caesalpinia sappan L.) Extract. Majalah Farmaseutik, 16(2), 125. https://doi.org/10.22146/farmaseutik.v16i2.48583

Shaikh, J. R., & Patil, M. (2020). Qualitative tests for preliminary phytochemical screening: An overview. International Journal of Chemical Studies, 8(2), 603–608. https://doi.org/10.22271/chemi.2020.v8.i2i.8834

Souhoka, F. A., Kapelle, I. B. D., & Sihasale, E. (2021). Phytochemical and Antioxidant Test of Binahong (Anredera cordifolia (Tenore) Steenis) Leaves Ethanol Extract. Fullerene Journal of Chemistry, 6(1), 28. https://doi.org/10.37033/fjc.v6i1.248

Wambaugh, M. A., Denham, S. T., Ayala, M., Brammer, B., Stonhill, M. A., & Brown, J. C. S. (2020). Synergistic and antagonistic drug interactions in the treatment of systemic fungal infections. ELife, 9, 1–26. https://doi.org/10.7554/eLife.54160

Ziklo, N., Tzafrir, I., Shulkin, R., & Salama, P. (2020). Salicylate UV-filters in sunscreen formulations compromise the preservative system efficacy against Pseudomonas aeruginosa and Burkholderia cepacia. Cosmetics, 7(3). https://doi.org/10.3390/COSMETICS7030063

Published
2022-12-25
How to Cite
Hafshah, M., Rohmah, A., & Mardliyah, A. (2022). Potential of Secang Wood (Caesalpinia sappan L.) Ethanol Extractas Anti-Oxidant and Sun-Protection . Al-Kimia, 10(2). https://doi.org/10.24252/al-kimia.v10i2.28619
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Article
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