Effectiveness of Spinach Leaf Extract (Amaranthus spinosus L.) as an Anti-inflammatory against Paw Edema of White Rats (Rattus norvegicus)
Abstrak
Pemanfaatan daun bayam duri (Amaranthus spinosus L.) dalam pengobatan tradisional banyak digunakan dikalangan masyarakat selain fungsinya sebagai bahan pangan. Daun bayam duri mengandung senyawa aktif yang dapat mengobati peradangan (inflamasi). Penelitian ini bertujuan untuk melihat pengaruh ekstrak daun bayam duri terhadap edema kaki tikus putih betina (Rattus norvegicus) yang diinduksi Karagenan. Metode penelitian yang digunakan adalah metode eksperiman dengan pola rancangan acak kelompok (RAK), yang terdiri dari 5 kali perlakuan dan 3 kali ulangan. Hasil penelitian menunjukan bahwa ekstrak daun bayam duri (Amaranthus spinosus L.) memberikan pengaruh yang signifikan terhadap penurunan peradangan (inflamasi) pada kaki tikus putih betina yang diinduksi karagenan. Efek antiinflamasi ekstrak daun bayam duri efektif pada dosis 1250 Mg/kg BB.
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Referensi
Alvarez-lorenzo, C., Blanco-fernandez, B., Puga, A. M., & Concheiro, A. (2013). Crosslinked ionic polysaccharides for stimuli-sensitive drug delivery ☆. Advanced Drug Delivery Reviews, 65(9), 1148–1171.
Buana, D. C., Sudiana, I. K., & Nugraha, J. (2019). The Potency Of Bay Leaves Extract (Syzygiumpolyanthum) As Anti-Inflammation In Rattus Norvegicus Induced With Complete Freund’s Adjuvant. Jurnal Teknologi Laboratorium, 8(2), 64–69. Https://Doi.Org/10.29238/Teknolabjournal.V8i2.177
Djindadi, I. T., Tulandi, S. S., Mongi, J., & Palandi, R. R. (2020). Aktivitas Antibakteri Daun Bayam Duri Amaranthus Spinosus Linn Terhadap Bakteri Staphylococcus Aureus. Majalah Info Sains, 1(2), 22–29. Https://Doi.Org/10.55724/Jis.V1i2.13 Fauzia, R. R., &
Zuniarto, A. A. (2018). Uji Efektivitas Antiinflamasi Suspensi Ekstrak Daun Bayam Duri (Amaranthus Spinosus L.) Terhadap Tikus Putih (Rattus Norvegicus) Yang Diinduksi Karagenan. Journal Of Holistic And Health Sciences, 1(2), 108–118. Https://Doi.Org/10.51873/Jhhs.V1i2.11 Mengie, T.,
Mequanente, S., Nigussie, D., Legesse, B., & Makonnen, E. (2021). Investigation Of Wound Healing And Antiinflammatory Activities Of Solvent Fractions Of 80% Methanol Leaf Extract Of Achyranthes Aspera L. (Amaranthaceae) In Rats. Journal Of Inflammation Https://Doi.Org/10.2147/Jir.S298244 Research, 14, 1775–1787.
Purnomo, F. O. (2023). Review Tanaman Bayam Berduri (Amaranthus Spinosus L.): Skrining Fitokimia Dan Pemanfaatannya. Binawan Student Journal, 5(1), 77–83.
Purwanto, E., Rajab, M. A., & Angraini, R. (2023). Potensi Kandungan Bahan-Bahan Alami Untuk Proses Penyembuhan Luka: Literatur Review. Jurnal Ilmiah Keperawatan Dan Kebidanan Holistic Care, 06(02), 18–25.
Rahma, K., & Nurcahyanti, O. (2021). Therapeutic Effect Of Red Spinach (Amaranthus Tricolor L.) Extract On Pancreatic Mda Levels Rats (Rattus Norvegicus) Exposed To Mld-Stz. Journal Of Biomedicine And Translational Research, 7(3), 129–133. Https://Doi.Org/10.14710/Jbtr.V7i3.12536
White, M. (1999). Mediators Of Inflammation And The Inflammatory Process. Journal Of Allergy And Clinical Immunology, 103(3), S378–S381.
Zweifach, B. W., Grant, L., & Mccluskey, R. T. (2014). The Inflammatory Process. Academic Press.
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