RASIO NEUTROFIL - LIMFOSIT SEBAGAI FAKTOR RISIKO KEMATIAN DAN LAMA RAWAT PADA SEPSIS NEONATORUM
Abstrak
Rasio neutrofil terhadap limfosit (NLR) merupakan penanda biologis yang mudah diakses dan telah dipelajari dalam berbagai kondisi klinis dan pada keadaan sepsis. Perubahan NLR dikaitkan dengan tingkat beratnya penyakit dan luarannya. Penelitian ini bertujuan untuk mengetahui apakah NRL dapat berfungsi sebagai penanda prognostik terhadap mortalitas/lama rawat inap pada sepsis neonatal. Penelitian kohort retrospektif ini meneliti hubungan antara NLR yang tinggi dengan mortalitas/lama rawat inap pada sepsis neonatorum pada neonatus yang dirawat di RSUP Dr. Wahidin Sudirohusodo Makassar dari Januari 2018 hingga Desember 2020. Pada penelitian ini didapatkan data dari 138 neonatus dengan rekam medis lengkap. Nilai NLR meningkat lebih besar seiring dengan angka mortalitas dan lama rawat inap kurang dari 7 hari. Tidak ada hubungan signifikan yang ditemukan antara NLR dan outcome pasien atau lama rawat inap. Penelitian ini tidak menemukan hubungan antara NLR dengan kematian atau lama rawat inap pada sepsis neonatal.
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