PEMANFAATAN EKSTRAK ETANOL KULIT RAMBUTAN (Nephelium lappaceum. L) SEBAGAI KRIM ANTIOKSIDAN

  • Hamsinah Hasan Universitas Islam Negeri Alauddin
    (ID)
  • M Ilham Tomagola
  • Suci Mayasari

Abstract

The rind of Rambutan was consumed by citizen just becomes waste.  Rambutan with Latin Nephelium lappaceum. L of the Sapindaceae tribe of the skin can be used as an antioxidant that has been stained by Thitilertdecha, et al mention that the phenolic component of the skin of rambutan fruit (Nephelium lappaceum L), among others, is geranin and corilagin is a group of flavonoids, and alegat acid from tannins class. Based on this, we will conduct research and formulate rambutan rind extract into cream preparations that have an antioxidant effect. The rambutan rind extract was obtained by using maseration method with 70% ethanolic and the viscous extract followed by testing of antioxidant activity by using DPPH method, obtained by IC50 22.774 μg / mL. The formula is varied with three emulgators. Formula I uses 2% TEA emulgator, Formula II Tween 80 and Span 80 3%, and 1% sodium lauryl sulphate. This antioxidant cream formula is physically tested for stability, including organoleptic test, emulsion type, pH measurement, viscosity measurement, forced conditions, homogeneity and flow type. Then proceed with testing the emulsion type of the cream preparation. The creamy formula of rambutan skin ethanol extract with a pharmaceutically stable 1% sodium lauryl sulfate emulgator

References

Ansel, H.C. (1989). Pengantar Bentuk Sediaan Farmasi edisi keempat. Jakarta : UI Press, 107-513

Ditjen POM Depkes RI.(1986): Formularium Kosmetika Indonesia, Depkes RI, Jakarta, 399-425.

Droge SL, Kombade S, Baviskar BA, Khadabadi SS. 2012. Photoprotective antioxidant phytochemicals. International Journal of Phytopharmacy, 2(3):72-76

Faradiba, Attamimi, F, Maulida. (2012). Formulasi Krim Wajah Dari Sari Buah Jeruk Lemon (Citrus limon L) dan Anggur Merah (Vitis vinivera L.) Dengan Variasi KOnsentrasi Emulgator. Fakultas Farmasi, Universitas Muslim Indonesia. Makassar.

Genaro, R.A. 1990. Remington’s Pharmaceutical Science. 18th ed. Macle Printing. Company, Easton-Pennisilva, USA

Mackiewicz. Z and Rimkevicius, A. (2008). Skin aging. Gerontologija, 9(2) : 103-108.

Masaki, H. (2010). Role of antioxidants in the Skin : Anti-aging effects. Journal of Dermatological Science, 58, 85-90.

Thitilertdecha, N., Teerawutgulrag., A., Rakariyatham, N. Antioksidant and Antibacterial activities of Nephelium lappacem I. extracts. Food Science and Technology. Elsivier. 2008; 1(17).

Winarsi Herry. (2007). Antioksidan Alami dan Radikal Bebas. Yogyakarta : Kanisus.

Wulandari, N. dan Lestari, S.R. 2012. The Potency of Rambutan (Nephelium lappaceum) Friut Peel Ethanolic Extract as an Antioxidat Natural Source Based on Viability Endotel Cell. Makalah disajika dalam Seminar Internasional Lifes Science, Laboratorium Sentral Ilmu Hayati

Published
2018-07-11
Abstract viewed = 1238 times