Pediculicidal Activity of Cem-ceman White Cempaka Flower (Michelia alba DC.) against Pediculus humanus capitis

Ahmad Fadli Robby; Iman Surya Pratama; Galuh Tresnani

doi:10.24252/djps.v4i1.21154

Ahmad Fadli Robby Program Studi Farmasi, Fakultas Kedokteran Universitas Mataram
(ID)
Iman Surya Pratama Program Studi Farmasi, Fakultas Kedokteran Universitas Mataram
Galuh Tresnani Program Studi Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mataram

DOI: https://doi.org/10.24252/djps.v4i1.21154

Abstract

The prevalence of pediculosis reported in Asia has ranged from 0.7% to 59%. High resistance and side effects is a challenge in using the pediculicidal agents. The widely use and empirical as well as scientific studies of traditional plants for anti-lice were already done, one of them is cempaka. The aim of this study was to determine the pediculicidal activity of cem-ceman white cempaka flower (Michelia alba DC.) on Pediculus humanus capitis in vitro. The white cempaka flowers made into cem-ceman preparations by mixing and soaking in coconut oil until 3 days. Pediculisidal activity was tested by filter paper diffusion test method with 3 replications. Data were analyzed using Kruskal-Wallis followed by post hoc Mann-Whitney Method test with software SPSS v.16. The phytochemical screening showed that sample contains alkaloid, tannin, saponin, and triterpenoid. Pediculidal activity test showed that cem-ceman white cempaka flower has pediculicidal effect in 10% concentration (w/v) with 66.67% mortality and 15% concentration (w/v) with 77.33% mortality. In conclusion cem-ceman white cempaka flowers has pediculicidal activity at concentration 10% and 15% but lower than permethrin 1% (p<0.05).

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