FORMULASI DAN UJI EFEKTIFITAS ANTIOKSIDAN KRIM EKSTRAK ETANOL KORTEKS KAYU JAWA (LANNEA COROMANDELICA HOUT MERR) DENGAN METODE DPPH

  • Isriany Ismail Jurusan Farmasi Fakultas Ilmu Kesehatan Universitas Islam Negeri Alauddin Makassar
  • Gemy Handayany
  • Armisman Paturusi
  • Watri Ratnasari

Abstract

The  research  has  conducted  the  formulation  and  Effectiveness  Test  Ethanol Extract Antioxidant Cream Wood Java cortex (Lannea Coromandelica hout Merr) by DPPH method. This study aims to determine the concentration of the extract java wood (Lannea Coromandelica hout Merr) is effective as an antioxidant for cream formula. Formula cream tested the effectiveness of antioxidants with DPPH. Ethanol extract of the wood cortex java cream formulated in dosage forms by using various concentration of extract 0.03%, 0.3%, 3%. Comparative antioxidant is vitamin C used at a concentration of 0.05%. The test results showed that all the cream formulation has antioxidant activity. Formula cream timber cortex extract Java (Lannea coromandelica Hout  Merr)  showed  antioxidant  activity  is  the  most  effective  formula  containing extracts of 3% with the percent inhibition of 55.39% compared with the creamy formula of vitamin C with the percent inhibition of 53.76%.

References

Ansel, H.C. Pengantar Bentuk Sediaan Farmasi, Edisi ke-4. Farida Ibrahim, penerjemah. Jakarta: UI Press.2008. Hal. 12

Joseph Stalin, A Study on the Antioxidant and Free Radical Scaveing Property of Lannea Coromandelica Bark Extract. Pharmaceutical Sciences. 2013. Hal. 4

Napat Prabmechai. Screening of Antioxidant, Antityrosinase and Antibacterial Activities from Extracts of Lannea coromandelica (Houtt.). Faculty of Pharmaceutical Sciences. Clinicallaboratory section,Khan Kaen University, Khan Kean, Thailand

Niken Widiastuti. Pengukuran Aktivitas Antioksidan dengan Metode CUPRAC, DPPH, dan FRAP serta korelasinya dengan Fenol dan Flavonoid pada enam tanaman. Fakultas MIPA. Bogor: Institut Pertanian Bogor. 2010. Hal. 9

Sjamsul A. 2010 Radikal bebas.pdf. http:// www.pediatrik.com 8 agustus jam 20.00 wita

Trifena. Analisis Uji In Vitro dan In Vivo Ekstrak Kombinasi Kulit Manggis dan Pegagan sebagai Krim Antioksidan. Skripsi Fakultas MIPA. Depok: Universitas Indonesia. 2010. Hal. 12

Wijaya, A. Radikal Bebas dan Parameter Status Antioksidan, Forum Diagnosticum, Prodia Diagnostic Educarional Services. 1996. Hal. 12

Published
2017-02-15
Abstract viewed = 636 times