The Synthesis and Characterization of Structural Properties of Hydroxyapatite from Cuttlefish Shell Using X-Ray Diffraction Method
##semicolon##
https://doi.org/10.24252/jpf.v12i2.50635
##semicolon##
Cangkang sotong;, Hidroksiapatit;, Kalsinasi;, Suhu;, XRD
Abstrak
Telah dilakukan pembuatan hidroksiapatit (HAp) padat dengan variasi suhu kalsinasi. Penelitian ini bertujuan untuk menentukan ukuran kristal, cacat material dan kadar kristalinitas HAp menggunakan XRD. HAp dibuat dengan mencampurkan serbuk cangkang sotong larutan KH2PO4, NaOH dan Aquades kemudian mengeringkannya selama 24 jam. Ekstraksi CaCO3 dari cangkang sotong dengan metode kalsinasi pada berbagai variasi suhu, yaitu 600 0C, 800 0C dan 1.000 0C. Uji XRD untuk menentukan nilai ukuran kristal, cacat kristal dan kristalinitas material HAp. Data XRD menunjukkan bawha padatan HAp terbentuk kristal yang berukuran semakin kecil (50,97 nm, 48,64 nm dan 36,52 nm) ketika suhu kalsinasi meningkat, cacat kristal semakin bertambah (0,38 nm-2.10-4, 0,42 nm-2.10-4 dan 0,74 nm-2.10-4) seiring bertambahnya suhu kalsinasi dan nilai kristalinitas berkurang (46,31 %, 39,06 % dan 37,93 %) berdasarkan perubahan suhu kalsinasi.
##plugins.generic.usageStats.downloads##
##plugins.generic.usageStats.noStats##
##submission.citations##
[1] S. Sunardi et al., “The Synthesized-Hydroxyapatite Powder from Anadara Granosa Shells using Deposition Time Method for Biomedical Applications,” Jurnal Ilmu Fisika. Vol. 16, No. 1, March 2024, pp. 88–96. 2024, https://doi.org/10.25077/jif.16.1.88-96.2024.
[2] P. Widiyanti, “Sintesis dan Karakterisasi Komposit Hidroksiapatit dari Tulang Sotong (Sepia sp.)-Kitosan untuk Kandidat Aplikasi Bone Filler”.
[3] S. John et al., “Toxicity of Natural Hydroxyapatite,” in Biomedical Engineering, vol. 23, P. Vizureanu and M. Simona Baltatu, Eds., IntechOpen, 2024. doi: 10.5772/intechopen.111654.
[4] F. Lebre, R. Sridharan, M. J. Sawkins, D. J. Kelly, F. J. O’Brien, and E. C. Lavelle, “The shape and size of hydroxyapatite particles dictate inflammatory responses following implantation,” Sci Rep, vol. 7, no. 1, p. 2922, Jun. 2017, doi: 10.1038/s41598-017-03086-0.
[5] C. K. Holley and M. A. Dobrovolskaia, “Innate Immunity Modulating Impurities and the Immunotoxicity of Nanobiotechnology-Based Drug Products,” Molecules, vol. 26, no. 23, p. 7308, Dec. 2021, doi: 10.3390/molecules26237308.
[6] M. Maruyama, “Hydroxyapatite clay used to fill the gap between implant and bone,” The Journal of Bone and Joint Surgery. British volume, vol. 77-B, no. 2, pp. 213–218, Mar. 1995, doi: 10.1302/0301-620X.77B2.7706333.
[7] S. Ferraris et al., “Bioactive materials: In vitro investigation of different mechanisms of hydroxyapatite precipitation,” Acta Biomaterialia, vol. 102, pp. 468–480, Jan. 2020, doi: 10.1016/j.actbio.2019.11.024.
[8] P. Kazimierczak and A. Przekora, “Osteoconductive and Osteoinductive Surface Modifications of Biomaterials for Bone Regeneration: A Concise Review,” Coatings, vol. 10, no. 10, p. 971, Oct. 2020, doi: 10.3390/coatings10100971.
[9] S. Ebrahimi, C. Stephen Sipaut@ Mohd Nasri, and S. E. Bin Arshad, “Hydrothermal synthesis of hydroxyapatite powders using Response Surface Methodology (RSM),” PLoS ONE, vol. 16, no. 5, p. e0251009, May 2021, doi: 10.1371/journal.pone.0251009.
[10] S. E. Cahyaningrum, N. Herdyastuty, B. Devina, and D. Supangat, “Synthesis and Characterization of Hydroxyapatite Powder by Wet Precipitation Method,” IOP Conf. Ser.: Mater. Sci. Eng., vol. 299, p. 012039, Jan. 2018, doi: 10.1088/1757-899X/299/1/012039.
[11] J. Zhu, D. Kong, Y. Zhang, N. Yao, Y. Tao, and T. Qiu, “The Influence of Conditions on Synthesis Hydroxyapatite By Chemical Precipitation Method,” IOP Conf. Ser.: Mater. Sci. Eng., vol. 18, no. 6, p. 062023, Oct. 2011, doi: 10.1088/1757-899X/18/6/062023.
[12] S. Gates-Rector and T. Blanton, “The Powder Diffraction File: a quality materials characterization database,” Powder Diffr., vol. 34, no. 4, pp. 352–360, Dec. 2019, doi: 10.1017/S0885715619000812.
[13] E. Fitriyanti, Utari, and B. Purnama, “Comparison XRD pattern of CoFe 2 O 4 thin films and nanoparticles,” J. Phys.: Conf. Ser., vol. 909, p. 012010, Nov. 2017, doi: 10.1088/1742-6596/909/1/012010.
[14] K. U. Henggu, B. Ibrahim, and P. Suptijah, “Hydroxyapatite Production from Cuttlebone as Bone Scaffold Material Preparations,” Jurnal PHPI, vol. 22, no. 1, p. 1, Apr. 2019, doi: 10.17844/jphpi.v22i1.25869.
[15] Herpandi, I. Widiastuti, Wulandari, and M. R. Aldino, “Utilization of Cuttlefish Bone as The Alternative Source of Heterogenic Alkali Catalyst,” IOP Conf. Ser.: Earth Environ. Sci., vol. 995, no. 1, p. 012058, Apr. 2022, doi: 10.1088/1755-1315/995/1/012058.
[16] A. Errich et al., “Toxic heavy metals removal using a hydroxyapatite and hydroxyethyl cellulose modified with a new Gum Arabic,” Indonesian J. Sci. Technol, vol. 6, no. 1, pp. 41–64, Jan. 2021, doi: 10.17509/ijost.v6i1.31480.
[17] H. Daupor, “Extraction of Hydroxyapatite by Alkaline Acid from Budu Waste and Synthesis Using Calcination Method,” J. Phys.: Conf. Ser., vol. 2049, no. 1, p. 012041, Oct. 2021, doi: 10.1088/1742-6596/2049/1/012041.
[18] Masruroh, A. B. Manggara, T. Lapailaka, and R. Triandi, “Penentuan Ukuran Kristal (Crystallite Size) Lapisan Tipis PZT Dengan Metode XRD Melalui Pendekatan Persamaan Debye Scherrer,” Erudio, vol. 1, no. 2, 2013, doi: 10.18551/erudio.1-2.4.
[19] J. Zarah, “Interpretasi Data Derajat Kristanilitas dan Ukuran Kristal Karbon Aktif Ampas Tebu Teraktivasi KOH, H3PO4, Na2S2O3, KMnO4,”.
[20] F. W. Puspita, “Synthesis And Characterization Of Hydroxyapatite From Shell Eggs Race Chicken (Gallus Gallus) Using Wet Deposition Method,” Journal of Chemistry , vol. 6, no. 1, 2017.
[21] C. Combes, S. Cazalbou, and C. Rey, “Apatite Biominerals,” Minerals, vol. 6, no. 2, p. 34, Apr. 2016, doi: 10.3390/min6020034.
[22] J. B. Franklin, B. Zou, P. Petrov, D. W. McComb, M. P. Ryan, and M. A. McLachlan, “Optimised pulsed laser deposition of ZnO thin films on transparent conducting substrates,” J. Mater. Chem., vol. 21, no. 22, p. 8178, 2011, doi: 10.1039/c1jm10658a.
[2] P. Widiyanti, “Sintesis dan Karakterisasi Komposit Hidroksiapatit dari Tulang Sotong (Sepia sp.)-Kitosan untuk Kandidat Aplikasi Bone Filler”.
[3] S. John et al., “Toxicity of Natural Hydroxyapatite,” in Biomedical Engineering, vol. 23, P. Vizureanu and M. Simona Baltatu, Eds., IntechOpen, 2024. doi: 10.5772/intechopen.111654.
[4] F. Lebre, R. Sridharan, M. J. Sawkins, D. J. Kelly, F. J. O’Brien, and E. C. Lavelle, “The shape and size of hydroxyapatite particles dictate inflammatory responses following implantation,” Sci Rep, vol. 7, no. 1, p. 2922, Jun. 2017, doi: 10.1038/s41598-017-03086-0.
[5] C. K. Holley and M. A. Dobrovolskaia, “Innate Immunity Modulating Impurities and the Immunotoxicity of Nanobiotechnology-Based Drug Products,” Molecules, vol. 26, no. 23, p. 7308, Dec. 2021, doi: 10.3390/molecules26237308.
[6] M. Maruyama, “Hydroxyapatite clay used to fill the gap between implant and bone,” The Journal of Bone and Joint Surgery. British volume, vol. 77-B, no. 2, pp. 213–218, Mar. 1995, doi: 10.1302/0301-620X.77B2.7706333.
[7] S. Ferraris et al., “Bioactive materials: In vitro investigation of different mechanisms of hydroxyapatite precipitation,” Acta Biomaterialia, vol. 102, pp. 468–480, Jan. 2020, doi: 10.1016/j.actbio.2019.11.024.
[8] P. Kazimierczak and A. Przekora, “Osteoconductive and Osteoinductive Surface Modifications of Biomaterials for Bone Regeneration: A Concise Review,” Coatings, vol. 10, no. 10, p. 971, Oct. 2020, doi: 10.3390/coatings10100971.
[9] S. Ebrahimi, C. Stephen Sipaut@ Mohd Nasri, and S. E. Bin Arshad, “Hydrothermal synthesis of hydroxyapatite powders using Response Surface Methodology (RSM),” PLoS ONE, vol. 16, no. 5, p. e0251009, May 2021, doi: 10.1371/journal.pone.0251009.
[10] S. E. Cahyaningrum, N. Herdyastuty, B. Devina, and D. Supangat, “Synthesis and Characterization of Hydroxyapatite Powder by Wet Precipitation Method,” IOP Conf. Ser.: Mater. Sci. Eng., vol. 299, p. 012039, Jan. 2018, doi: 10.1088/1757-899X/299/1/012039.
[11] J. Zhu, D. Kong, Y. Zhang, N. Yao, Y. Tao, and T. Qiu, “The Influence of Conditions on Synthesis Hydroxyapatite By Chemical Precipitation Method,” IOP Conf. Ser.: Mater. Sci. Eng., vol. 18, no. 6, p. 062023, Oct. 2011, doi: 10.1088/1757-899X/18/6/062023.
[12] S. Gates-Rector and T. Blanton, “The Powder Diffraction File: a quality materials characterization database,” Powder Diffr., vol. 34, no. 4, pp. 352–360, Dec. 2019, doi: 10.1017/S0885715619000812.
[13] E. Fitriyanti, Utari, and B. Purnama, “Comparison XRD pattern of CoFe 2 O 4 thin films and nanoparticles,” J. Phys.: Conf. Ser., vol. 909, p. 012010, Nov. 2017, doi: 10.1088/1742-6596/909/1/012010.
[14] K. U. Henggu, B. Ibrahim, and P. Suptijah, “Hydroxyapatite Production from Cuttlebone as Bone Scaffold Material Preparations,” Jurnal PHPI, vol. 22, no. 1, p. 1, Apr. 2019, doi: 10.17844/jphpi.v22i1.25869.
[15] Herpandi, I. Widiastuti, Wulandari, and M. R. Aldino, “Utilization of Cuttlefish Bone as The Alternative Source of Heterogenic Alkali Catalyst,” IOP Conf. Ser.: Earth Environ. Sci., vol. 995, no. 1, p. 012058, Apr. 2022, doi: 10.1088/1755-1315/995/1/012058.
[16] A. Errich et al., “Toxic heavy metals removal using a hydroxyapatite and hydroxyethyl cellulose modified with a new Gum Arabic,” Indonesian J. Sci. Technol, vol. 6, no. 1, pp. 41–64, Jan. 2021, doi: 10.17509/ijost.v6i1.31480.
[17] H. Daupor, “Extraction of Hydroxyapatite by Alkaline Acid from Budu Waste and Synthesis Using Calcination Method,” J. Phys.: Conf. Ser., vol. 2049, no. 1, p. 012041, Oct. 2021, doi: 10.1088/1742-6596/2049/1/012041.
[18] Masruroh, A. B. Manggara, T. Lapailaka, and R. Triandi, “Penentuan Ukuran Kristal (Crystallite Size) Lapisan Tipis PZT Dengan Metode XRD Melalui Pendekatan Persamaan Debye Scherrer,” Erudio, vol. 1, no. 2, 2013, doi: 10.18551/erudio.1-2.4.
[19] J. Zarah, “Interpretasi Data Derajat Kristanilitas dan Ukuran Kristal Karbon Aktif Ampas Tebu Teraktivasi KOH, H3PO4, Na2S2O3, KMnO4,”.
[20] F. W. Puspita, “Synthesis And Characterization Of Hydroxyapatite From Shell Eggs Race Chicken (Gallus Gallus) Using Wet Deposition Method,” Journal of Chemistry , vol. 6, no. 1, 2017.
[21] C. Combes, S. Cazalbou, and C. Rey, “Apatite Biominerals,” Minerals, vol. 6, no. 2, p. 34, Apr. 2016, doi: 10.3390/min6020034.
[22] J. B. Franklin, B. Zou, P. Petrov, D. W. McComb, M. P. Ryan, and M. A. McLachlan, “Optimised pulsed laser deposition of ZnO thin films on transparent conducting substrates,” J. Mater. Chem., vol. 21, no. 22, p. 8178, 2011, doi: 10.1039/c1jm10658a.
Diterbitkan
2024-12-08
Terbitan
Bagian
Articles
##submission.copyrightStatement##
##submission.license.cc.by4.footer##
