Formulation and Antibacterial Activity of Porang (Amorphophallus muelleri Blume) Extract Gel Against Propionibacterium acne
Keywords:
Porang tubers, gel, Propionibacterium acne, formulation, antibacterial activity
Abstract
Introduction: The increase in bacterial resistance to antibiotics provides an opportunity to obtain antibacterial compounds from natural ingredients. Porang is a plant belonging to the Araceae family that has potential against Propionibacterium acne. Aims: This study aims to determine the effectiveness of the preparation of porang tuber extract gel against Propionibacterium acne. Methods: The porang were extraction by maceration using ethanol. The extract porang were made gel with various concentration and evaluation their stability and antibacterial activity using disc diffusion method. Result: The hedonic test showed no significant differenece each of formula and stable during storage in two weeks. On the other hand, only formula F2 and F3 can inhibit of Propionibacterium acnee. Conclusion: The porang extract can made of gel and good stability. The formula F2 and F3 have antibacterial activity.
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References
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Sarlina, Razak, A. R., & Tandah, M. R. (2017). Antibacterial Activity Test of Lemongrass Leaf Extract Gel Preparations (Cymbopogon nardus L. Rendle) against Staphylococcus aureus Bacteria that Causes Acne. Galenika Pharmacy Journal (Galenika Journal of Pharmacy), Volume 3 Number 2. Pages. 143 – 149.
Savira, H. G., & Trimulyono, G. (2021). Antibacterial Activity of Bacterial Isolate from Porang Tuber (Amorphophallus muelleri) Against Escherichia coli and Staphylococcus aureus. Unesa Journal, Volume 10 Number 3. Hal. 347-355.
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Anggriani, D., & et al. (2013). Anti-acne Gel Formulation from Gambir Ethyl Acetate Extract. Indonesian Pharmaceutical Research Journal, Volume 1 Number 2. Hal. 62-66.
Ansel. (1989). Introduction to Pharmaceutical Dosage Forms, Translation: Farida Ibrahim,. Issue 4. Jakarta: UI Press.
CE, R., Magadum, G. S., Nadaf, M. A., S.V, Y., & M, M. (2011). Phytochemical Screening of The Rhizomes of Kaempferia Galanga. International Journal of Pharmacognosy and Phytochemical Research, Volume 3 Number 3, Pages 61-63 ISSN: 0975 4873.
Dea, Rise, & Sri. (2019). Effect of pH on the Stability of Alpha Arbutin in Niosom Gel. Pharmaceutical Magazine, Vol. 16 No. 1. Pg: 91-100.
Erlina, M., & Muhtadi. (2021). Antibacterial Activity Test of Porang (Amorphophallus Muelleri Blume), Suweg (Amorphophallus Paeoniifolius), Iles-Iles and Walur (Amorphophallus Campanulatus) Tuber Extracts Against Pseudomonas Aeruginosa. The 13th University Research Colloquium.
Evi, & et al. (2018). Test of Phytochemical Characteristics and Antioxidant Activity of Robusta Coffee Beans (Coffea canephora Pierre) from Bogor, Bandung and Garut using the DPPH method. Fitofarmaka Pharmaceutical Scientific Journal, Volume 8 Number 1. Pages 59-66.
Hasanah, N., & et al. (2020). Comparison of Formulation and Physical Stability Test of Aloe Vera Gel with Different Concentrations. Edu Masda Journal, Vol. 4 No.2 Pg. 132-144.
Hindun, S., & et al. (2021). Formulation and Activity Test of Sweet Orange Leaf Extract Gel (Citrus x aurantium L.) Against Propionibacterium acnes Bacteria. FITOFARMAKA : Pharmaceutical Scientific Journal, Volume 11 Number 2, Hal. 109-117.
Husni, P., & et al. (2021). Sabdarifarma Journal. Physical Stability Test of Gel ethanol extract of purple sweet potato leaves (Ipomoea batatas (L.) Lamk), Vol 3 No.1 Hal. 1-5.
Irianto, I.D. (2020). Antibacterial Activity and Physical Properties Test of Green Betel Decoct Gel (Piper betle L.) as an Alternative Treatment for Cow Mastitis. Pharmaceutical Magazine, Vol. 16 No. 2 Pgs 202-210.
Lestari, E., & Lagiono. (2018). Utilization of Plants as Medicine by the Community of Karang Dukuh Village, Belawang District, Barito Kuala Regency. Journal of Biology, Volume 4 Number 3, Pages 114-119.
Sani, L. M., Subaidah, W. A., & Andayani, Y. (2021). Formulation and evaluation of physical characters of ethanol extract gel preparations of bay leaves (Syzygium polyanthum). Sasambo Journal of Pharmacy, Volume 2, Number 1, Pg. 16-22.
Sarlina, Razak, A. R., & Tandah, M. R. (2017). Antibacterial Activity Test of Lemongrass Leaf Extract Gel Preparations (Cymbopogon nardus L. Rendle) against Staphylococcus aureus Bacteria that Causes Acne. Galenika Pharmacy Journal (Galenika Journal of Pharmacy), Volume 3 Number 2. Pages. 143 – 149.
Savira, H. G., & Trimulyono, G. (2021). Antibacterial Activity of Bacterial Isolate from Porang Tuber (Amorphophallus muelleri) Against Escherichia coli and Staphylococcus aureus. Unesa Journal, Volume 10 Number 3. Hal. 347-355.
Wahyuddin, M., Kurniati, A., & Aridewi, G. A. (2018). The Effect of Carbopol Concentration on Physical Stability of Noni Fruit Extract Mask Preparations as Anti-Acne. . JF FKIK UINAM, Volume 6 Number 1, Page. 25-33.
Yasin, I., & et al. (2021). Exploring the Potential of Porang Plants as Cultivation Plants in the Community Forest System (HkM) of North Lombok Regency. Journal of Service Master of Science Education, Volume 4, Number 3, p. 316-327.
Published
2023-07-31
How to Cite
Tahar, N., Wahyuni, D., Adawiyah, R., Khaerani, & Wahyuddin, M. (2023). Formulation and Antibacterial Activity of Porang (Amorphophallus muelleri Blume) Extract Gel Against Propionibacterium acne. Ad-Dawaa’ Journal of Pharmaceutical Sciences, 6(1), 83-92. https://doi.org/10.24252/djps.v6i1.38744
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